An R package for power and boundary calculations in pre-licensure vaccine trials using a sequential generalized likelihood ratio test


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Documentation for package ‘sglr’ version 0.7

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sglr-package An R package for power and boundary calculations in pre-licensure vaccine trials using a sequential generalized likelihood ratio test
computeBoundary A function to compute the boundary of the decision region in terms of the number of adverse events (AEs) of interest, such as vaccine AEs.
glrSearch This function searches through a space of design boundaries (scalar values a and b) to find values that achieve close to specified type I and type II errors for the sequential generalized likelihood ratio test of p0 versus p1 (specified respectively as vector of length 2) in pre-licensure vaccine trials
plotBoundary A function to plot the boundary of the decision region
sglr An R package for power and boundary calculations in pre-licensure vaccine trials using a sequential generalized likelihood ratio test
sglrWebapp A function to run a web application to compute boundaries and plotting the decision region