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| MedianaDesigner-package | Efficient Simulation-Based Power and Sample Size Calculations for a Broad Class of Late-Stage Clinical Trials |
| ADPopSel | Simulation-based design of adaptive trials with data-driven population selection |
| ADPopSelApp | Graphical user interface to design an adaptive trial with data-driven population selection |
| ADPopSelC | Simulation-based design of adaptive trials with data-driven population selection |
| ADPopSelExample1 | Simulation-based design of an adaptive trial with population selection (normally distributed endpoint) |
| ADPopSelExample2 | Simulation-based design of an adaptive trial with population selection (binary endpoint) |
| ADPopSelExample3 | Simulation-based design of an adaptive trial with population selection (time-to-event endpoint) |
| ADPopSelReportDoc | Simulation report |
| ADPopSelSingleCore | Simulation-based design of adaptive trials with data-driven population selection |
| ADRand | Simulation-based design of adaptive trials with response-adaptive randomization |
| ADRandApp | Graphical user interface to design an adaptive trial with data-driven population selection |
| ADRandC | Simulation-based design of adaptive trials with response-adaptive randomization |
| ADRandExample | Simulation-based design of dose-finding Phase II trials with response-adaptive randomization (normally distributed endpoint) |
| ADRandReportDoc | Simulation report |
| ADRandSingleCore | Simulation-based design of adaptive trials with response-adaptive randomization |
| ADSSMod | Simulation-based design of adaptive trials with data-driven sample size or event count re-estimation |
| ADSSModApp | Graphical user interface to design an adaptive trial with data-driven sample size or event count re-estimation |
| ADSSModC | Simulation-based design of adaptive trials with data-driven sample size or event count re-estimation |
| ADSSModExample1 | Simulation-based design of an adaptive trial with sample size re-estimation (normally distributed endpoint) |
| ADSSModExample2 | Simulation-based design of an adaptive trial with sample size re-estimation (binary endpoint) |
| ADSSModExample3 | Simulation-based design of an adaptive trial with event count re-estimation (time-to-event endpoint) |
| ADSSModReportDoc | Simulation report |
| ADSSModSingleCore | Simulation-based design of adaptive trials with data-driven sample size or event count re-estimation |
| ADTreatSel | Simulation-based design of adaptive trials with data-driven treatment selection |
| ADTreatSelApp | Graphical user interface to design an adaptive trial with data-driven treatment selection |
| ADTreatSelC | Simulation-based design of adaptive trials with data-driven treatment selection |
| ADTreatSelExample1 | Simulation-based design of an adaptive trial with treatment selection (normally distributed endpoint) |
| ADTreatSelExample2 | Simulation-based design of an adaptive trial with treatment selection (binary endpoint) |
| ADTreatSelExample3 | Simulation-based design of an adaptive trial with treatment selection (time-to-event endpoint) |
| ADTreatSelReportDoc | Simulation report |
| ADTreatSelSingleCore | Simulation-based design of adaptive trials with data-driven treatment selection |
| ComputeDRFunctionParameters | Simulation-based design of adaptive trials with response-adaptive randomization |
| DRFunction | Simulation-based design of adaptive trials with response-adaptive randomization |
| EventPred | Simulation-based event prediction in trials with an event-driven design |
| EventPredApp | Graphical user interface for event prediction in trials with an event-driven design |
| EventPredData | Example data set for EventPred |
| EventPredEventCount | Simulation-based event prediction in trials with an event-driven design |
| EventPredExample | Simulation-based event prediction in trials with an event-driven design (time-to- event endpoint) |
| EventPredPriorDistribution | Calculation of the parameters of prior gamma distributions |
| EventPredR | Simulation-based event prediction in trials with an event-driven design |
| EventPredReportDoc | Simulation report |
| EventPredRSingleCore | Simulation-based event prediction in trials with an event-driven design |
| FutRule | Simulation-based selection of an optimal futility stopping rule at an interim analysis |
| FutRuleApp | Graphical user interface for an optimal selection of a futility stopping rule at an interim analysis |
| FutRuleC | Simulation-based selection of an optimal futility stopping rule at an interim analysis |
| FutRuleExample1 | Simulation-based selection of an optimal futility stopping rule (normally distributed endpoint) |
| FutRuleExample2 | Simulation-based selection of an optimal futility stopping rule (binary endpoint) |
| FutRuleExample3 | Simulation-based selection of an optimal futility stopping rule (time-to-event endpoint) |
| FutRuleReportDoc | Simulation report |
| FutRuleSingleCore | Simulation-based selection of an optimal futility stopping rule at an interim analysis |
| GenerateReport | Simulation report |
| MedianaDesigner | Efficient Simulation-Based Power and Sample Size Calculations for a Broad Class of Late-Stage Clinical Trials |
| MultAdj | Simulation-based design of traditional trials with multiple objectives |
| MultAdj1SingleCore | Simulation-based design of traditional trials with multiple objectives |
| MultAdjApp | Graphical user interface for power calculations in traditional trials with multiple objectives |
| MultAdjC | Simulation-based design of traditional trials with multiple objectives |
| MultAdjExample1 | Simulation-based power calculations in Phase III trials with multiple dose-placebo comparisons |
| MultAdjExample2 | Simulation-based power calculations in Phase III trials with multiple endpoints |
| MultAdjExample3 | Simulation-based power calculations in Phase III trials with multiple endpoints and multiple dose-placebo comparisons |
| MultAdjReportDoc | Simulation report |
| print.ADPopSelResults | Simulation report |
| print.ADRandResults | Simulation report |
| print.ADSSModResults | Simulation report |
| print.ADTreatSelResults | Simulation report |
| print.EventPredResults | Simulation report |
| print.FutRuleResults | Simulation report |
| print.MultAdjResults | Simulation report |
| ReportDoc | Simulation report |