High Dimensional Penalized Generalized Linear Mixed Models (pGLMM)


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Documentation for package ‘glmmPen’ version 1.5.1.8

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adaptControl Control of Metropolis-within-Gibbs Adaptive Random Walk Sampling Procedure Controls the adaptive random walk Metropolis-within-Gibbs sampling procedure.
basal Basal dataset: A composition of cancer datasets with top scoring pairs (TSPs) as covariates and binary response indicating if the subject's cancer subtype was basal-like. A dataset composed of four datasets combined from studies that contain gene expression data from subjects with several types of cancer. Two of these datasets contain gene expression data for subjects with Pancreatic Ductal Adenocarcinoma (PDAC), one dataset contains data for subjects with Breast Cancer, and the fourth dataset contains data for subjects with Bladder Cancer. The response of interest is whether or not the subject's cancer subtype was the basal-like subtype. See articles Rashid et al. (2020) "Modeling Between-Study Heterogeneity for Improved Replicability in Gene Signature Selection and Clinical Prediction" and Moffitt et al. (2015) "Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma" for further details on these four datasets.
BIC.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
coef.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
coef.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
family.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
fitted.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
fitted.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
fit_dat Fit a Penalized Generalized Mixed Model via Monte Carlo Expectation Conditional Minimization (MCECM) 'fit_dat' is used to fit a penalized generalized mixed model via Monte Carlo Expectation Conditional Minimization (MCECM) for a single tuning parameter combinations and is called within 'glmmPen' or 'glmm' (cannot be called directly by user)
fixef.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
fixef.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
formula.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
formula.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
glFormula_edit Extracting Useful Vectors and Matrices from Formula and Data Information
glmm Fit a Generalized Mixed Model via Monte Carlo Expectation Conditional Minimization (MCECM)
glmmPen Fit Penalized Generalized Mixed Models via Monte Carlo Expectation Conditional Minimization (MCECM)
glmmPen_FineSearch Fit a Penalized Generalized Mixed Model via Monte Carlo Expectation Conditional Minimization (MCECM) using a finer penalty grid search 'glmmPen_FineSearch' finds the best model from the selection results of a 'pglmmObj' object created by 'glmmPen', identifies a more targeted grid search around the optimum lambda penalty values, and performs model selection on this finer grid search.
lambdaControl Control of Penalization Parameters and Selection Criteria
LambdaSeq Calculation of Penalty Parameter Sequence (Lambda Sequence)
logLik.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
logLik.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
model.frame.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
model.frame.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
model.matrix.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
model.matrix.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
ngrps.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
nobs.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
optimControl Control of Penalized Generalized Linear Mixed Model Fitting Constructs the control structure for the optimization of the penalized mixed model fit algorithm.
pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
pglmmObj-class Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
pglmmObj-method, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
plot.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
plot.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
plot_mcmc Plot Diagnostics for MCMC Posterior Draws of the Random Effects
predict.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
predict.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
print.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
print.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
ranef.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
ranef.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
residuals.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
residuals.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
selectControl Control of Penalization Parameters and Selection Criteria
select_tune Fit a Sequence of Penalized Generalized Mixed Model via Monte Carlo Expectation Conditional Minimization (MCECM) 'select_tune' is used to fit a sequence of penalized generalized mixed models via Monte Carlo Expectation Conditional Minimization (MCECM) for multiple tuning parameter combinations and is called within 'glmmPen' (cannot be called directly by user)
show, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
sigma.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
sigma.pglmmObj, Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'
sim.data Simulates data to use for the 'glmmPen' package Simulates data to use for testing the 'glmmPen' package. Possible parameters to specify includes number of total covariates, number of non-zero fixed and random effects, and the magnitude of the random effect covariance values.
summary.pglmmObj Class 'pglmmObj' of Fitted Penalized Generalized Mixed-Effects Models for package 'glmmPen'