Description

Provides details such as Morphine Equivalent Dose (MED), brand name and opioid content which are calculated of all oral opioids authorized for sale by Health Canada based on their Drug Identification Number (DIN). MEDs are calculated based on recommendations by Canadian Institute for Health Information (CIHI) and information obtained from Health Canada’s Drug Product Database’s monthly data dump. Please note in no way should output from this package be a substitute for medical advise.
All medications should only be consumed on prescription from a licensed healthcare provider

Functions

Loading/updating the Health Canada dataset

library(OralOpioids)
HealthCanada_Opioid_Table <- load_HealthCanada_Opioid_Table(filelocation = tempdir())
## No HealthCanada_Opioid_Tables are currently in the filelocation. Do you want to download  the latest data from Health Canada? (y/n)  
## 
## 1: Y
## 2: N
## 
## Selection: Y
## trying URL 'https://www.canada.ca/content/dam/hc-sc/documents/services/drug-product-database/allfiles.zip'
## Content type 'application/zip' length unknown
## downloaded 1.4 MB
## 
## trying URL 'https://www.canada.ca/content/dam/hc-sc/documents/services/drug-product-database/allfiles_ap.zip'
## Content type 'application/zip' length unknown
## downloaded 407 KB
## 
## trying URL 'https://www.canada.ca/content/dam/hc-sc/documents/services/drug-product-database/allfiles_dr.zip'
## Content type 'application/zip' length unknown
## downloaded 317 KB
## 
## trying URL 'https://www.canada.ca/content/dam/hc-sc/documents/services/drug-product-database/allfiles_ia.zip'
## Content type 'application/zip' length unknown
## downloaded 4.9 MB
## 
## The HealthCanada_Opioid_Table was successfully updated to 2023-01-03.
## DISCLAIMER: Not a substitute for medical advise. Please note that the output generated by the package should not be substituted for clinical advise and any medication ## should be only consumed at the advise of a licensed healthcare provider.
## 
## Source url of the data: https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database/what-data-extract-drug-product-database.html
## Source url used for dosing: https://www.cihi.ca/sites/default/files/document/opioid-prescribing-canada-trends-en-web.pdf
head(HealthCanada_Opioid_Table)
##       DIN MED_per_dispensing_unit Base1 Base2 Base3             Opioid      Route   Form                       Brand No_tabs/ml assuming 50 MED limit per day
## 1 2517175  Couldn't be calculated     1     N       BUPRENORPHINE 2 MG SUBLINGUAL TABLET TARO-BUPRENORPHINE/NALOXONE                   Couldn't be calculated
## 2 2517175  Couldn't be calculated     1     N          NALOXONE 0.5 MG SUBLINGUAL TABLET TARO-BUPRENORPHINE/NALOXONE                   Couldn't be calculated
## 3 2517183  Couldn't be calculated     1     N       BUPRENORPHINE 8 MG SUBLINGUAL TABLET TARO-BUPRENORPHINE/NALOXONE                   Couldn't be calculated
## 4 2517183  Couldn't be calculated     1     N            NALOXONE 2 MG SUBLINGUAL TABLET TARO-BUPRENORPHINE/NALOXONE                   Couldn't be calculated
## 5 2518759                       5     1     N           TRAMADOL 50 MG       ORAL TABLET           JAMP TRAMADOL HCL                                       10
## 6  763527                     1.2     1     N             CODEINE 8 MG       ORAL TABLET            ORADRINE TABLETS                                       42
##   No_tabs/ml assuming 90 MED limit per day Maximum No_tabs/ml assuming 50 MED limit for 7 days Maximum No_tabs/ml assuming 50 MED limit for 14 days
## 1                   Couldn't be calculated                              Couldn't be calculated                               Couldn't be calculated
## 2                   Couldn't be calculated                              Couldn't be calculated                               Couldn't be calculated
## 3                   Couldn't be calculated                              Couldn't be calculated                               Couldn't be calculated
## 4                   Couldn't be calculated                              Couldn't be calculated                               Couldn't be calculated
## 5                                       18                                                  70                                                  140
## 6                                       75                                                 294                                                  588
##   Maximum No_tabs/ml assuming 50 MED limit for 30 days              Status_1 last_updated
## 1                               Couldn't be calculated              APPROVED   2023-01-03
## 2                               Couldn't be calculated              APPROVED   2023-01-03
## 3                               Couldn't be calculated              APPROVED   2023-01-03
## 4                               Couldn't be calculated              APPROVED   2023-01-03
## 5                                                  300              APPROVED   2023-01-03
## 6                                                 1260 CANCELLED POST MARKET   2023-01-03

Get the Morphine Equivalent Dose (MED) from Health Canada by using the DIN

MED(786535,HealthCanada_Opioid_Table)
## [1] 5

Get the Brand name from Health Canada by using the DIN

Brand(786535, HealthCanada_Opioid_Table)
## [1] "DILAUDID"

Get the Opioid content from Health Canada by using the DIN

Opioid(786535,HealthCanada_Opioid_Table)
## [1] "HYDROMORPHONE 1 MG"

Get the Maximum number of units/millilitres of oral opioids allowed per day assuming a daily limit of 50 MED/day for a DIN from the HealthCanada Opioid Table by using the DIN

MED_50(786535,HealthCanada_Opioid_Table)
[1] 10

Get the Maximum number of units/millilitres of oral opioids allowed per day assuming a daily limit of 90 MED/day for a DIN from the HealthCanada Opioid Table by using the DIN

MED_90(786535,HealthCanada_Opioid_Table)
[1] 18