PRSPGx: Construct PGx PRS

Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ”Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods” by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).

Version: 0.1.0
Depends: R (≥ 4.0.0)
Imports: gglasso (≥ 1.5.0), SGL (≥ 1.3.0), glmnet (≥ 4.0.2), bigsnpr (≥ 1.5.2), Matrix (≥ 1.2.18), GIGrvg (≥ 0.5.0), MCMCpack (≥ 1.4.6), bdsmatrix (≥ 1.3.4), bigsparser (≥ 0.4.0), lmtest (≥ 0.9.37), mvtnorm (≥ 1.1.0), propagate (≥ 1.0.6), bigparallelr (≥ 0.2.3), methods (≥ 3.6.3), bigstatsr (≥ 1.2.3)
Suggests: knitr, rmarkdown
Published: 2021-12-15
Author: Song Zhai [aut, cre]
Maintainer: Song Zhai <zsviolet1993 at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: PRSPGx results

Documentation:

Reference manual: PRSPGx.pdf
Vignettes: Put the title of your vignette here

Downloads:

Package source: PRSPGx_0.1.0.tar.gz
Windows binaries: r-devel: PRSPGx_0.1.0.zip, r-release: PRSPGx_0.1.0.zip, r-oldrel: PRSPGx_0.1.0.zip
macOS binaries: r-release (arm64): PRSPGx_0.1.0.tgz, r-oldrel (arm64): PRSPGx_0.1.0.tgz, r-release (x86_64): PRSPGx_0.1.0.tgz, r-oldrel (x86_64): PRSPGx_0.1.0.tgz

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