Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD) models described by differential equation (DE) systems. Simulation using ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015) <doi:10.1016/j.vascn.2015.03.004>).
| Version: | 1.3.0 |
| Depends: | R (≥ 3.0.2) |
| Imports: | Rcpp (≥ 0.12.9), BH, data.table, stringr, MASS, randtoolbox, jsonlite, stats, parallel, magrittr |
| LinkingTo: | BH, Rcpp (≥ 0.12.9) |
| Suggests: | httr, testthat (≥ 3.0.0), mockery, knitr, rmarkdown |
| Published: | 2023-03-02 |
| Author: | Ron Keizer [aut, cre], Jasmine Hughes [aut], Dominic Tong [aut], Kara Woo [aut], InsightRX [cph, fnd] |
| Maintainer: | Ron Keizer <ron at insight-rx.com> |
| License: | MIT + file LICENSE |
| URL: | https://github.com/InsightRX/PKPDsim, https://insightrx.github.io/PKPDsim/ |
| NeedsCompilation: | yes |
| Materials: | README NEWS |
| In views: | MixedModels |
| CRAN checks: | PKPDsim results |
| Reference manual: | PKPDsim.pdf |
| Vignettes: |
Covariates Absorption models Export model Model Output Parameters Regimen Simulation Speed |
| Package source: | PKPDsim_1.3.0.tar.gz |
| Windows binaries: | r-devel: PKPDsim_1.3.0.zip, r-release: PKPDsim_1.3.0.zip, r-oldrel: PKPDsim_1.3.0.zip |
| macOS binaries: | r-release (arm64): PKPDsim_1.3.0.tgz, r-oldrel (arm64): PKPDsim_1.3.0.tgz, r-release (x86_64): PKPDsim_1.3.0.tgz, r-oldrel (x86_64): PKPDsim_1.3.0.tgz |
| Old sources: | PKPDsim archive |
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